Medical Mycology Society of Nigeria

August 9, 2018

MMSN members, Drs Nick Irhurhe and Rita Oladele served on a 33-member expert international panel that convened to develop a workable definition of chronic pulmonary aspergillosis for resource-constrained countries.

Their recommendations have been published in this online report in the CDC journal ‘Emerging Infectious Diseases’.

In summary, the following are required to make a diagnosis of CPA

1. Symptoms for 3 months or longer (haemoptysis and/or persistent cough, and/or weight loss) (other symptoms are common, but not required, notably fatigue, chest pain, breathlessness and sputum production)

AND

2. Radiological features (progressive cavitation on chest imaging AND/OR intracavitary fungal ball AND/OR pleural thickening or pericavitary fibrosis or infiltrates all adjacent to cavities)

AND

 3. Microbiological evidence of Aspergillus infection (positive Aspergillus-specific IgG and/or sputum microscopy showing hyphae consistent with Aspergillus and/or Aspergillus growth on 2 or more sputum or other respiratory samples)